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pucG [2017-8-11 16:0:3]
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pucG [2017-8-11 16:0:3]

(S)-ureidoglycine-glyoxylate aminotransferase
Locus
BSU32520
Isoelectric point
5.42
Molecular weight
45.58 kDa
Protein length
416 aa Sequence Blast
Gene length
1248 bp Sequence Blast
Function
purine utilization
Product
(S)-ureidoglycine-glyoxylate aminotransferase
Essential
no
Synonyms
yurG

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,341,166 → 3,342,416

The protein

Catalyzed reaction/ biological activity

  • transamination between an unstable intermediate ((S)-ureidoglycine) and the end product of purine catabolism (glyoxylate) to yield oxalurate and glycine PubMed
  • Protein family

  • class-V pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Structure

    Expression and Regulation

    Operons

    Genes
    Description

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
  • Regulatory mechanism

  • PucR: activation, PubMed, in PucR regulon
  • Regulation

  • induced in the presence of purine nucleotides (inducer: allantoin) (PucR) PubMed
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    Biological materials

    Mutant

  • MGNA-A942 (yurG::erm), available at the NBRP B. subtilis, Japan
  • References

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